Following the launch of the “pro-aging“- inspired skincare brand FRAME® – www.framecosmetics.com – that seeks to offer a 360 degrees skin care and wellness ritual according to the teachings of the Mediterranean culture of wellness – VOS Group – www.vosgroup.it/en – reflected on the success of its creation and set its sights on a project that would ultimately bring dermocosmetics into a new, revolutionary realm of skin care science: the creation of mìsula®. The founding of the Frame brand had already established a step further in innovation within the sphere of skin care, in terms of philosophy, approach, science, and formulation and production of cosmetic products. In terms of philosophy, FRAME® shifted the discourse of “anti-aging” to a “pro-aging” approach to reflect the awareness that the way we perceive our age does actually influence the way we live. In terms of approach, FRAME® insisted on the fact that without internal wellness, external beauty is impossible to achieve, and thus it established a wellness-oriented skin care regimen based on: Cosmeceuticals, Nutraceuticals, Supplements, Vitamins, Herbal Extracts and Mechanobiological Devices. Now, building on years of collaboration with its Scientific Advisory Board (SAB) and leveraging on its own experience and expertise gained from over 30 years as a sector leader,  VOS Group has brought to life its most ambitious scientific and creative endeavor yet: mìsula®. This “sister” brand to FRAME® is essentially a condensed but highly specialized collection of skin care products that take dermocosmetics even farther. 

ABOUT CHRONOBIOLOGY & CIRCADIAN RHYTHMS

The cyclical nature of time affects virtually all aspects of our being and is the basis of the underlying rhythmicity which is typical of our lives. To “tell time”, most living organisms use internal timing mechanisms known as “biological clocks”. These “clocks”coordinate our physiological and behavioral functions and interactions with our environment. One of the strongest influences on rhythmicity is the solar day… 

 

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ABOUT CHRONOBIOLOGY OF THE SKIN

All life on earth and each organ in our body follows circadian rhythms that revolve around the 24-hour light/dark cycle. You are probably not aware that your skin follows its own circadian rhythm, but this cycle determines every action of your skin cells from the growth of new tissue to damage repair…

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ABOUT BARRIER FUNCTION RHYTHMS:

The skin has its own chronobiological rhythms. It is even one of the first circadian rhythms to develop in children. At birth, children do not know a day lasts 24 hours, which explains why they do not sleep through the night, but their skin acquires its circadian variations very early, in particular as regards hydration…

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ABOUT SKIN ANTI-AGING STRATEGIES

Skin aging is a complex biological process influenced by a combination of endogenous  (intrinsic) and exogenous (extrinsic) factors. Since skin health and beauty is considered one of the principal factors that represent overall “well-being” and the perception of “health” in humans, several anti-aging strategies have been developed during recent years…

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ABOUT PHOTOPROTECTION & SYSTEMIC ANTIOXIDANTS

Chronic photo-damage of the skin manifests itself as extrinsic skin aging (photo-aging). DNA photodamage and UV-generated reactive oxygen species (ROS) are the initial molecular events that lead to most of the typical histological and clinical manifestations of chronic photodamage of the skin…

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ABOUT DEREGULATION OF THE SKIN’S CIRCADIAN RHYTHM

Stress, jetlag, shift working hours, intense lifestyles and even exposure to blue light emissions from the screens of ubiquitous electronic devices such as laptops, tablets and mobile phones, disrupt the body’s circadian clock, which leads to the deregulation of the skin’s circadian rhythm. As a consequence, the skin essentially becomes “lost in time,” showing signs of fatigue and becoming more prone to external aggressors…

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The world of natural skincare is constantly growing and changing. We are dedicated to providing our customers with only top-tier products, based on the most current scientific knowledge. Ours is a fresh approach to luxury skincare: when using Mediterranean botanical ingredients in their purest form leveraging the power of nature within the context of science and offering products that are not only good for your skin, but also good for our planet. From developing new products to developing new processes, innovation is central to how we work and grow on a daily basis. Our ambition is to become the most conscientious and influential natural skincare company in the world, and we can achieve this by expanding our knowledge in all aspects of skincare, educating and empowering consumers, inspiring and sharing our passion in others, being ethical, responsible, and principled in all aspects of our business. 

mìsula® magazine


THIS IS SOMETHING THAT YOU NEED TO KNOW ABOUT PORES:

Do you know it’s totally fine and normal to have visible pores on your face? One of the most common skin complaints in beauty forums, dermatologists’ offices, and my friends’ text messages is large pores. But the truth is that everyone has pores on their face—and they are almost always visible! The Instagram-ready airbrushed look that we’ve come to assume means “good, healthy skin” is usually a fiction of makeup and photo editing. Here’s what your pores actually do for you, how to tell if your pores are normal, and how to take action, if needed.
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IS WOMEN SKINCARE SO DIFFERENT FROM MEN’S SKINCARE ?

It's a question you've probably asked yourself while deliberating over which grooming products to buy. Do you really need a different set of cleansers and creams than your girlfriend? Are the products that claim to be created specially for men a gimmick or perhaps just women's skin or hair care packaged in a black bottle and finished off with a scent of smoke and leather? If you've been buying said products, don't worry:
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THE BENEFITS OF D-VITAMIN

We clearly need vitamin D from sunshine to maintain health, but no one knowingly wants to be put at risk of developing cancer. So how do we go about balancing the risks? What should we be doing to look after both our skin and our general health? Vitamin D is a fat-soluble vitamin essential for maintaining bone health. Shahir Hamdulay, consultant physician and rheumatologist at The Wellington Hospital in London, explains: “Deficiency of vitamin D is highly prevalent worldwide and attributed in part to inadequate sunlight exposure.”
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THE INCI NAME GAME

Can you imagine if consumers read cosmetic product labels disclosing full chemical names rather than general INCIs? Based on the current chemophobic environment, nothing would sell; not even life's most essential element: dihydrogen monoxide (H2O). But such nomenclature generali­zations seem to have initiated the vicious cycle (and yet human behavior) of lumping what appears to be like-for-like into categories of "good" and "bad" ingredients; in my view, perpetuating the free-from cosmetic phenomenon.
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THE SCIENCE OF HOW YOUR BODY AGES

Ask people what they think they’ll look like in 25 years, and chances are they’ll mention how their parents looked at that age. And while genetics certainly play a part, research shows there’s more to the story. Only about 30% of what we see as aging is inherited, explains John Rowe, M.D., Julius B. Richmond Professor of Health Policy and Aging at Columbia Mailman School of Public Health. When you look specifically at things above the neck — like cognitive function, vision, and hearing — that number goes up to about 50%.
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WHAT CAUSES ITP (Idiopathic Thrombocytopenic Purpura)?

If you’ve ever discovered a mysterious bruise on your body, you’ve probably tried to retrace your steps. Maybe you slammed into that doorknob harder than you thought, or maybe stumbling to the bathroom in the dark for a midnight pee break was a bad idea. But if you have the bleeding disorder immune thrombocytopenia (also known as idiopathic thrombocytopenic purpura or just ITP), you might find yourself wondering where the hell this new bruise came from way too often.
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